Dielectrophoretic characterization and separation of metastatic variants of small cell lung cancer cells
نویسندگان
چکیده
In this study, the ability of Dielectrophoresis (DEP) to recognize phenotypic variants of small cell lung cancer (SCLC) cells has been tested. The phenotypic variations of the SCLC cells are associated with the cell-surface decorations, which in turn, provide the cells with antiadhesive properties allowing detachment from the primary tumour and the subsequent metastatic spread of such tumours. Dielectrophoretic separation chambers have been used to sort the phenotypes and so form a cytometric tool for the analysis, identification and monitoring of tumour heterogeneity.
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